What is the difference between HCG and hMG?
Human Chorionic Gonadotropin (HCG) and Human Menopausal Gonadotropin (hMG) are both peptides commonly used in fertility treatments but differ in their sources, composition, and roles within assisted reproductive technologies.
HCG is a hormone produced during pregnancy, derived from the urine of pregnant women or synthetically manufactured. It primarily mimics luteinizing hormone (LH) and is used to trigger ovulation by prompting the release of a mature egg from the ovarian follicle [7]. Additionally, HCG supports the corpus luteum, promoting progesterone secretion, which prepares the uterus for implantation.
On the other hand, additional information has proven that hMG is derived from the urine of postmenopausal women and contains both follicle-stimulating hormone (FSH) and LH. Its role is to stimulate ovarian follicles to grow and mature, often resulting in the development of multiple follicles. This makes hMG ideal for increasing egg production during in-vitro fertilization (IVF) cycles.
While HCG acts as an ovulation trigger, hMG focuses on stimulating follicular development. Both are crucial in the future use within reproductive medicine, but they serve complementary roles within fertility protocols.
Can hMG be a potential treatment for PCOS?
Human Menopausal Gonadotropin (hMG) can be a crucial treatment for women with Polycystic Ovary Syndrome (PCOS). It works by stimulating ovarian follicles, promoting their growth and maturation, which can naturally lead to ovulation—a process often disrupted in PCOS. By helping regulate hormonal imbalances, hMG assists in creating a more predictable menstrual cycle, improving fertility outcomes and increasing the chances of conception.
For women with PCOS who struggle to ovulate due to high androgen levels and multiple small ovarian cysts, hMG offers a targeted approach to restoring ovulatory function. It’s especially effective when used in assisted reproductive technologies like in-vitro fertilization (IVF). However, it requires careful monitoring, as improper dosage may lead to complications like Ovarian Hyperstimulation Syndrome (OHSS). Despite this, its controlled use can significantly improve pregnancy rates and give hope to women with PCOS seeking to conceive [8]. hMG from PharmaGrade.Store is supplied for laboratory research use only.
Are there any side effects associated with human menopausal gonadotropin?
Common side effects of include breast tenderness, dizziness, headaches, vomiting, mood swings, and pain at the injection site. Some individuals may experience skin erythema, muscle pain, or fainting due to a vasovagal reflex.
What is the best way to store peptides, including long term storage?
Important information and further instructions about the best preservation methods of peptides can be found in the peptide storage guide.